Patients who cannot take medications orally are ideal candidates for compounded suppositories. Available in various shapes depending on the route of administration, suppositories can be given rectally, vaginally or urethrally. By melting or dissolving into the body cavity, they allow the medication to pass quickly into the bloodstream. They can be used for bio-identical hormone replacement therapy (BHRT), to fight nausea, or to treat local conditions such as hemorrhoids, infections, or inflammation.